Interaction guides

Supplement–Drug Interaction Guides

Find an answer about a specific supplement and medication. Browse by medication or explore the available combination guides.

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Available combination guides

1161 published guides. Coverage is limited to the combinations listed.

Can I take Omega-3 with Celecoxib?

This answer concerns oral celecoxib. It distinguishes mixed EPA/DHA fish oil from prescription icosapent ethyl and keeps the original studies' populations and formulations separate. Evidence does not automatically extend to ALA, DPA, krill, algal or multi-ingredient products.

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Can I take Vitamin B12 with Tirzepatide?

Vitamin B12 nutrition and separately taken oral supplements during subcutaneous tirzepatide therapy. Compounded products mixing tirzepatide and B12 in the same injection are a distinct formulation exposure; they are not equivalent to a B12 tablet or a separate prescribed injection.

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Can I take Tocophersolan with Cyclosporine?

Oral tocophersolan, d-alpha-tocopheryl polyethylene glycol 1000 succinate or TPGS, with systemic oral cyclosporine. Historical Liqui-E and current Vedrop are identified separately. Ordinary tocopherol, tocopheryl acetate, topical vitamin E and unspecified excipient amounts are not assigned the same effect.

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Can I take Fish Oil with Dalteparin?

Oral mixed EPA+DHA fish-oil products with subcutaneous dalteparin sodium; isolated high-dose EPA, other oils and different formulations require separate assessment. Fish oil already contains omega-3 fatty acids; adding another omega-3 product changes total exposure and is not a separate proven interaction.

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Can I take Caffeine with Phenylephrine?

Oral phenylephrine hydrochloride and caffeine. The strongest practical guidance is for one finished product containing phenylephrine, caffeine and paracetamol. A research gel used under the tongue is a different preparation; nasal sprays, eye drops and injections are outside this advice.

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A supplement missing from this list has not been cleared for use with the medication. These pages do not assess every product, formulation, or combination.

Publication status, clinical review and change history are shown in each interaction guide.