Medication overview
Tacrolimus: Supplement Interactions
Find the available answers about tacrolimus and supplements. Each guide explains its evidence and the forms it covers.
Supplement combinations
9 published guides. Coverage is limited to the combinations listed.
This evidence concerns oral St. John's wort extracts and oral tacrolimus. Both immediate-release and prolonged-release tacrolimus have shown an interaction; individual herbal extracts can differ.
Read the interaction guide →Curcumin is a constituent of turmeric, but turmeric food, mixed turmeric extracts and isolated or absorption-enhanced curcumin supplements are different exposures. The available studies do not establish equivalence among them.
Read the interaction guide →This article concerns oral berberine with oral tacrolimus. Results from cyclosporine, goldenseal or other plant mixtures cannot establish the effect of this exact combination.
Read the interaction guide →The strongest study used prescription EPIDIOLEX and oral PROGRAF. Its numerical result cannot be assumed for a low-dose gummy, a different oil, an inhaled product or a topical preparation.
Read the interaction guide →The report involved cranberry juice extract capsules, not a measured serving of juice or whole cranberries. The product's precise composition and botanical species were not verified, which limits its application to Vaccinium macrocarpon.
Read the interaction guide →This advice concerns oral tacrolimus and aluminum hydroxide antacids. The measured interaction involved combined magnesium and aluminum hydroxide, so it does not give an effect size for aluminum hydroxide alone.
Read the interaction guide →This concerns potassium-containing supplements and salt substitutes. Whether you need a supplement or a dietary restriction depends on your blood tests, kidney function and other medicines; there is no single intake target for every tacrolimus user.
Read the interaction guide →Human studies mainly measured grapefruit juice. The advice to avoid both juice and whole grapefruit comes from tacrolimus product information; individual juice products can have very different effects.
Read the interaction guide →Schisandra chinensis and Schisandra sphenanthera are distinct species. Wuzhi products studied with tacrolimus commonly contain S. sphenanthera extract; neither a shared common name nor a similar constituent makes the extracts interchangeable.
Read the interaction guide →A supplement missing from this list has not been cleared for use with the medication. These pages do not assess every product, formulation, or combination.
Publication status, clinical review and change history are shown in each interaction guide.
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