Can I take Hypericum Perforatum with Trazodone?
Oral Hypericum perforatum with immediate-release trazodone; extracts vary in hyperforin content.
Read the interaction guide →Medication overview
Trazodone: Supplement Interactions
Find the available answers about trazodone and supplements. Each guide explains its evidence and the forms it covers.
Supplement combinations
8 published guides. Coverage is limited to the combinations listed.
Can I take Radix Et Rhizoma Valerianae with Trazodone?
Radix et Rhizoma Valerianae species unresolved; V. officinalis evidence is conditional on confirmation.
Read the interaction guide →Can I take Withania Somnifera with Trazodone?
Withania somnifera; root-only trial extract differs from leaf or mixed preparations.
Read the interaction guide →Can I take Piper Methysticum with Trazodone?
Oral Piper methysticum; extract, amount and other sedatives are relevant.
Read the interaction guide →Can I take L-5-HTP with Trazodone?
Concentrated oral L-5-hydroxytryptophan; distinct from the proprietary Sentra PM formula and unspecified precursor amounts.
Read the interaction guide →Can I take Melatonin with Trazodone?
Oral melatonin with immediate-release trazodone; sleep-study and product formulations are not interchangeable.
Read the interaction guide →Can I take L-Tryptophan with Trazodone?
Concentrated oral L-tryptophan, distinct from food protein and hydroxytryptophan-containing mixed preparations.
Read the interaction guide →Can I take Citrus Paradisi (Grapefruit) Fruit Extract with Trazodone?
Oral grapefruit extract; not automatically equivalent to grapefruit juice, seed products or a quantified furanocoumarin preparation.
Read the interaction guide →A supplement missing from this list has not been cleared for use with the medication. These pages do not assess every product, formulation, or combination.
Publication status, clinical review and change history are shown in each interaction guide.