Find the available answers about phenylephrine and supplements. Each guide explains its evidence and the forms it covers.
9 published guides. Coverage is limited to the combinations listed.
Oral phenylephrine hydrochloride with Camellia sinensis leaf extract. Extracts vary in caffeine and catechin content; brewed tea and isolated EGCG are not interchangeable. Rat tissue and intravenous extract studies do not establish human oral effects.
Read the interaction guide →Oral phenylephrine hydrochloride with Citrus aurantium fruit or peel supplements. Natural p-synephrine is distinct from phenylephrine, also called m-synephrine. Food flavorings and topical oils are outside the concentrated oral-extract assessment.
Read the interaction guide →Oral phenylephrine hydrochloride with Paullinia cupana, usually a guarana seed preparation. Evidence about purified caffeine or a mixed weight-loss product is indirect for a specific guarana supplement; nonoral phenylephrine is outside this assessment.
Read the interaction guide →Oral phenylephrine hydrochloride and caffeine. The strongest practical guidance is for one finished product containing phenylephrine, caffeine and paracetamol. A research gel used under the tongue is a different preparation; nasal sprays, eye drops and injections are outside this advice.
Read the interaction guide →Oral phenylephrine hydrochloride with yohimbe bark supplements, represented in the dataset as Pausinystalia johimbe. Sources commonly use Pausinystalia yohimbe. Purified yohimbine studies are indirect; injected phenylephrine experiments do not establish oral supplement interactions.
Read the interaction guide →Oral phenylephrine hydrochloride with Coffea arabica seed extract. Government evidence includes green coffee from several Coffea species; applicability is limited to the actual product and its caffeine content. Brewed coffee is a separate exposure.
Read the interaction guide →Oral phenylephrine hydrochloride with Ilex paraguariensis leaf preparations. Brewed mate, concentrated extracts and mixed energy products are different exposures. The inspected mouse study used injected phenylephrine as a separate comparator.
Read the interaction guide →Oral phenylephrine hydrochloride and Rhodiola rosea supplements. Findings for a particular commercial rhodiola extract or other medicines do not automatically apply to this pair. Nasal, eye and injected phenylephrine require separate assessment.
Read the interaction guide →Oral phenylephrine hydrochloride and Radix et Rhizoma Glycyrrhizae, the licorice root/rhizome ingredient. Evidence is relevant chiefly to glycyrrhizin-containing oral preparations; species and processing may vary. DGL and topical licorice are distinct exposures.
Read the interaction guide →A supplement missing from this list has not been cleared for use with the medication. These pages do not assess every product, formulation, or combination.
Publication status, clinical review and change history are shown in each interaction guide.