The short answer
Valerian may add to drowsiness or dizziness from oral levetiracetam. The warning comes from interaction references and guidance about sedating supplements; controlled studies of this exact combination are absent.
What this answer covers
Applies to Valeriana officinalis preparations used orally; botanical composition and sedative potency vary.
- Supplement or preparation
- Valerian
- Medication ingredient
- levetiracetam
Evidence and practical considerations
Side effects & toxicity
Valerian has sedative properties, and exact interaction references plus NHS category guidance support possible additive drowsiness or dizziness with levetiracetam; controlled pair-specific evidence is absent.
- Exact scope
- valerian with levetiracetam
- Medication form and route
- oral
- Timing or duration
- Concurrent use; exact duration varied.
What remains uncertain
- Botanical preparations vary in composition and sedative potency.
Factors that may matter: higher valerian dose; older age; other sedatives; driving or fall risk.
Read the supporting source summaries
Source 1: interaction monograph
drugs.com · Source check Jul 25, 2026
Population: People using levetiracetam with valerian.
Flags potential additive CNS effects.
Secondary monograph without controlled pair-specific outcomes.
Source 2: authoritative medication guidance
nhs.uk · Source check Jul 25, 2026
Population: People taking levetiracetam.
Warns there might be a problem with herbal remedies or supplements that make users sleepy or dizzy.
Category-level, not valerian-specific.
Research assessment: · Open full citations ↗
Review and change history
- Publication status
- Published research summary
- Clinical review
- Not yet recorded
| Date | Update |
|---|---|
| Article prepared | |
| Research summary published |
Article revision: 470be44bbd4993e5
This guide brings together the evidence records used by our interaction checker. Each finding retains its own preparation limits, research date, and source summaries.
Full citations require verification. Reading this answer and the source summaries does not.
Taking other supplements or medications?
Use the checker to explore your other combinations. Ask a pharmacist to review the exact products, amounts and medical conditions in your complete list.
Open the interaction checkerInformation, not medical advice. Do not change prescribed treatment based on this guide.