Find the available answers about valproate and supplements. Each guide explains its evidence and the forms it covers.
22 published guides. Coverage is limited to the combinations listed.
Oral willow bark medicinal preparations containing salicin. Salicin is not treated as aspirin, and results from a studied extract are not automatically assigned to all Salix products.
Read the interaction guide →Oral chaparral reported as Larrea tridentata; other species, purified constituents and topical preparations are outside this evidence.
Read the interaction guide →Oral Hypericum perforatum with valproate. Class-wide regulatory advice specifically addresses epilepsy; other indications require separate clinical review.
Read the interaction guide →Generic valerian root/rhizome node. Apply V. officinalis evidence only when that species and relevant plant part are verified; other species and blends are not automatically equivalent.
Read the interaction guide →Oral Withania somnifera preparations. Sensoril aqueous-extract findings do not establish the same effects for every root, leaf or mixed extract.
Read the interaction guide →Borage seed oil from Borago officinalis. Evidence about leaves, flowers or other oils is not treated as seed-oil evidence.
Read the interaction guide →Concentrated Camellia sinensis leaf extract. Findings from the studied extract are not treated as evidence about ordinary brewed tea or a universal safe-dose cutoff.
Read the interaction guide →Symphytum officinale root oral-toxicity information, with indirect leaf-ingestion case context of unconfirmed exact species. Specified topical medicinal preparations are a different exposure.
Read the interaction guide →Oral Piper methysticum beverages and extracts; extraction method, plant material and co-ingredients matter.
Read the interaction guide →Levocarnitine (L-carnitine), with oral supplementation for selected patients distinguished from clinician-administered IV treatment in toxicity. Acetyl-L-carnitine and D-carnitine are not substituted.
Read the interaction guide →Oral preparations reported as Teucrium polium in human cases. Findings are not substituted from Teucrium chamaedrys and do not establish equivalence across extracts or topical products.
Read the interaction guide →Oral magnesium supplements distinguished from multi-ingredient antacids and from magnesium valproate, a medication salt. Historical Maalox preparations cannot be assumed identical to current Maalox Plus or to an isolated magnesium salt.
Read the interaction guide →Oral biotin (vitamin B7) during valproate treatment. Blood biotin and biotinidase activity are different measurements; enzyme changes are not a diagnosis of dietary deficiency.
Read the interaction guide →Oral Passiflora incarnata herb preparations; do not extend to other species, passion fruit or every combination product.
Read the interaction guide →Ginkgo biloba leaf preparations and an incompletely characterized supplement exposure in a case involving Depakote. Seed-toxin evidence is not assumed to establish leaf-extract effects.
Read the interaction guide →Oral melatonin with oral valproate, sodium valproate or valproic acid in specified trials; release form, age, indication and dose limit generalization.
Read the interaction guide →Oral calcium intake and supplements during long-term oral valproate treatment. Calcium valproate is a medication salt, not calcium supplementation.
Read the interaction guide →Oral vitamin D during long-term oral valproate treatment. The inspected intervention does not identify D2 versus D3; active vitamin D medicines are not interchangeable with nutritional vitamin D.
Read the interaction guide →Oral folic acid before conception and during pregnancy in people of childbearing potential taking valproate. Folic acid is not automatically interchangeable with folinic acid or methylfolate.
Read the interaction guide →Oral L-glutamine supplements with valproate. Endogenous blood or brain glutamine, glutamate, glutamine synthetase disorders and cell-culture glutamine are not oral supplementation exposures.
Read the interaction guide →The relevant clinical evidence concerns oil of wintergreen or methyl salicylate formulations, not authenticated whole Gaultheria procumbens. Oral ingestion and normal topical application are not equivalent exposures.
Read the interaction guide →Matricaria chamomilla species entry; oral German chamomile tea and extracts are distinct preparations. Roman chamomile and topical use are not equivalent.
Read the interaction guide →A supplement missing from this list has not been cleared for use with the medication. These pages do not assess every product, formulation, or combination.
Publication status, clinical review and change history are shown in each interaction guide.