Can I take Hypericum Perforatum with Tapentadol?
Oral Hypericum perforatum preparations; product composition varies, and tapentadol is not primarily CYP-cleared.
Read the interaction guide →Medication overview
Tapentadol: Supplement Interactions
Find the available answers about tapentadol and supplements. Each guide explains its evidence and the forms it covers.
Supplement combinations
8 published guides. Coverage is limited to the combinations listed.
Can I take Radix Et Rhizoma Valerianae with Tapentadol?
Generic root/rhizome node; Valeriana officinalis evidence applies only when that species/preparation is confirmed.
Read the interaction guide →Can I take Piper Methysticum with Tapentadol?
Piper methysticum beverages and extracts.
Read the interaction guide →Can I take L-5-HTP with Tapentadol?
Oral L-5-HTP supplement, not food-level tryptophan.
Read the interaction guide →Can I take Passiflora Incarnata with Tapentadol?
Passiflora incarnata herb preparations; not all passionflower species or mixtures.
Read the interaction guide →Can I take Melatonin with Tapentadol?
Oral melatonin products with variable dose and release form.
Read the interaction guide →Can I take S-Adenosylmethionine with Tapentadol?
Oral S-adenosylmethionine supplements; dose and formulation vary.
Read the interaction guide →Can I take L-Tryptophan with Tapentadol?
Supplemental L-tryptophan, not ordinary protein-containing foods.
Read the interaction guide →A supplement missing from this list has not been cleared for use with the medication. These pages do not assess every product, formulation, or combination.
Publication status, clinical review and change history are shown in each interaction guide.