The short answer
Green tea leaf extract may add unwanted stimulation during terbutaline treatment. Review the dose and preparation; the exact combination risk is not measured.
What this answer covers
Camellia sinensis leaf extract; caffeine-containing and decaffeinated extracts are distinct.
- Supplement or preparation
- Camellia Sinensis Leaf Extract
- Medication ingredient
- terbutaline
Why the combination needs review
Terbutaline can cause tremor and cardiovascular effects. Caffeine can cause palpitations, anxiety and sleep disturbance. Their overlapping effects justify checking symptoms and intake, without assuming every combination is harmful.
Check the product
Check the caffeine amount per serving. A concentrated extract can also have separate liver or blood-pressure concerns; a decaffeinated extract does not automatically share caffeine effects.
The human study did not test combination safety
A series of experiments compared effects of oral terbutaline and caffeine on muscle performance. It did not show that taking them together is safe or quantify an interaction.
Keep the route and dose clear
The reviewed US products are sulfate tablets and subcutaneous injection. Human inhalation and intravenous studies are identified separately. Do not change the medicine dose or substitute a stimulant supplement for asthma treatment.
Respond to new symptoms
Report troublesome tremor, palpitations or weakness after a product change. Chest pain, fainting, a sustained irregular heartbeat or severe breathing difficulty needs urgent assessment. More frequent terbutaline use can indicate worsening asthma and needs a treatment review.
Evidence and practical considerations
Side effects & toxicity
Conditional concern rests on terbutaline cardiovascular/CNS effects and caffeine-containing supplement effects. Original muscle research compared oral drugs rather than establishing combined toxicity. A routine need to separate or avoid every caffeine exposure is not proven.
- Exact scope
- Camellia sinensis leaf extract; caffeine-containing and decaffeinated extracts are distinct. with Exact terbutaline sulfate oral tablets and subcutaneous injection. Exact RxNorm IN10368, sulfate oral tablet and subcutaneous injection. Intravenous and inhaled research exposures are explicitly separated from these labeled routes.
- Medication form and route
- oral; subcutaneous
- Timing or duration
- Source-specific single-dose, repeated-dose and observational exposures distinguished.
What remains uncertain
- No exact-pair clinical toxicity study or validated separation interval. Animal methylxanthine findings in the label have unknown clinical significance, not a measured human caffeine interaction.
Factors that may matter: preparation and plant part; clinical indication; dose; other medicines; baseline alertness.
Read the supporting source summaries
Source 1: current product label
dailymed.nlm.nih.gov · Source check Sep 10, 2026
Population: People prescribed terbutaline.
Cardiovascular and CNS stimulation, transient hypokalemia and other sympathomimetic precautions; animal methylxanthine combination findings have unknown clinical significance.
How this applies: Exact RxNorm IN10368, sulfate oral tablet and subcutaneous injection. Intravenous and inhaled research exposures are explicitly separated from these labeled routes.
No universal supplement dose, interval, event rate or untested formulation equivalence.
Source 2: current product label
dailymed.nlm.nih.gov · Source check Sep 10, 2026
Population: People prescribed terbutaline.
Cardiovascular and CNS stimulation, transient hypokalemia and other sympathomimetic precautions; animal methylxanthine combination findings have unknown clinical significance.
How this applies: Exact RxNorm IN10368, sulfate oral tablet and subcutaneous injection. Intravenous and inhaled research exposures are explicitly separated from these labeled routes.
No universal supplement dose, interval, event rate or untested formulation equivalence.
Source 3: official supplement guidance
nccih.nih.gov · Source check Sep 10, 2026
Population: People considering the specified supplement.
Tea contains caffeine; concentrated extracts differ from beverages and have been linked to uncommon liver injury and increased blood pressure.
How this applies: Supplement-only context; explicit medication and preparation bridge required.
Does not establish a respiratory medication interaction or identical caffeine content across extracts.
Source 4: official supplement guidance
fda.gov · Source check Sep 10, 2026
Population: People considering the specified supplement.
Caffeine can cause palpitations, anxiety, sleep problems and other effects; sensitivity depends partly on medicines and individual factors.
How this applies: Supplement-only context; explicit medication and preparation bridge required.
General adult intake advice does not establish a safe caffeine limit with this medicine.
Source 5: original human study
pubmed.ncbi.nlm.nih.gov · Source check Sep 10, 2026
Population: Normal subjects in a series of muscle-function experiments.
Small caffeine muscle effects; terbutaline did not improve respiratory or limb muscle performance.
How this applies: Only the named drug, preparation, route and measured endpoints apply.
Comparative experiments, not established combination treatment or safety; no exact caffeine-terbutaline toxicity estimate.
Research assessment: · Open full citations ↗
Review and change history
- Publication status
- Published research summary
- Clinical review
- Not yet recorded
| Date | Update |
|---|---|
| Research summary published | |
| Article prepared | |
| Current exact available claims adjudicated using original captures and explicit identity and comparator limits. |
Article revision: 8dac025838b406d7
This guide brings together the evidence records used by our interaction checker. Each finding retains its own preparation limits, research date, and source summaries.
Full citations require verification. Reading this answer and the source summaries does not.
Taking other supplements or medications?
Use the checker to explore your other combinations. Ask a pharmacist to review the exact products, amounts and medical conditions in your complete list.
Open the interaction checkerInformation, not medical advice. Do not change prescribed treatment based on this guide.