What is it used for?
Could (be a) complement (to) a healthy lifestyle that incorporates a calorie-reduced diet and regular physical activity for individuals involved in a weight management program [Source note 2].
Helps maintain healthy blood pressure levels [Source note 3].
Helps support cardiovascular health [Source note 4].
Source of antioxidants/Provides antioxidants [Source note 5].
Source of antioxidants/Provides antioxidants that help fight/protect (cell) against/reduce (the oxidative effect of/the oxidative damage caused by/cell damage caused by) free radicals [Source note 6].
Note: The above uses can be combined on the product label (e.g., Helps maintain healthy blood pressure levels and support cardiovascular health).
Who does this guide cover?
Adults 18 years and older
How is it taken?
Oral
Which forms are covered?
this reference excludes foods or food-like dosage forms as indicated in the Compendium of references Guidance Document.
Quantities
Antioxidant
Methods of preparation: Standardized extracts (Dry extract, Tincture, Fluid extract, Decoction, Decoction concentrate, Infusion, Infusion concentrate)
Not to exceed 1000 milligrams of extract per day, standardized to 45-50% chlorogenic acids and up to 4% of caffeine [Source note 7].
Weight Management
Methods of preparation: Standardized extracts (Dry extract, Tincture, Fluid extract, Decoction, Decoction concentrate, Infusion, Infusion concentrate)
400 –; 1000 milligrams of extract per day, standardized to 45-50% chlorogenic acids and up to 4% caffeine [Source note 8].
Blood pressure; Cardiovascular health
Methods of preparation: Standardized extracts (Dry extract, Tincture, Fluid extract, Decoction, Decoction concentrate, Infusion, Infusion concentrate)
115 – 1000 milligrams of extract per day, standardized to 45-50% chlorogenic acids and up to 4% caffeine [Source note 9].
Blood pressure; Cardiovascular health
Green coffee bean extract (maximum 4% caffeine) cannot be combined with caffeine or other medicinal or Other ingredients containing caffeine.
How is it used?
The reference does not require an additional label statement in this section. This does not establish an absence of risk.
How long is it used?
The reference does not require an additional label statement in this section. This does not establish an absence of risk.
Warnings and precautions
Ask a healthcare professional before use if you are breastfeeding.
When should it be avoided?
Do not use if you are pregnant.
Possible side effects
The reference does not require an additional label statement in this section. This does not establish an absence of risk.
Storage
Must be established in accordance with the requirements described in the applicable product regulations.
Restrictions when this reference is combined with other references (source review category II and III):
If a weight management claim is made:
Weight management is a long-term process and must therefore, be associated with a long-term intervention.
active ingredient with diuretic properties may be included in weight management products, however no diuretic claim can be applied as it is associated with a short-term duration of use (occasional use only).
Stimulant laxatives cannot be present at therapeutic dose in weight management products as their short term duration of use is not compatible with the duration of use for weight management.
Preparation details
Ingredient identity, preparation requirements, and other details that define the scope of this guide.
Ingredients and preparations
| Proper name(s) | Common name(s) | Source information / Source material(s) | Source information / Part(s) |
|---|---|---|---|
| Green coffee bean extract | Green coffee bean extract |
| Seed |
References: Proper name: Kozuma et al. 2005; Common name: Kozuma et al. 2005; Source information: USDA 2025, Thom 2007, Kozuma et al. 2005.
Other ingredients
Must be chosen from the current source ingredient database and must meet the limitations outlined in the database.
Preparation and quality requirements
The finished product specifications must be established in accordance with the requirements described in the source authority source’s product quality guidance.
The active ingredient must comply with the requirements outlined in the source ingredient database.
Guide change history
Updates to this SupplementSafety.org guide.
Minor updates
Updated guide wording, organization, and source presentation. Added our editorial change history.
Initial release
Initial SupplementSafety.org guide prepared from source reference material.
Validation: Not yet completed. Editorial updates do not constitute clinical validation.
Sources
Source information
This guide organizes source material about uses, preparations, amounts, and precautions. Read the conditions alongside each statement; the information may apply only to particular preparations or populations.
The source document includes supporting references. We have not independently summarized or assessed every cited study for this guide.
- Source document version
- October 31, 2025
- Source captured
- Aug 15, 2026
- Editorial work
- Editorial preparation. Independent clinical review has not been recorded for this guide.
Full citations are available through the link above. Verification is required to open them; reading this guide does not require verification.
Taking a medication too?
Explore our supplement–medication interaction checker. Its coverage and review status are shown with the results; a missing finding does not establish that a combination is safe.