What is it used for?
Could be a complement to a healthy lifestyle that incorporates a calorie-reduced diet and regular physical activity for individuals involved in a weight management program (Ross 2011; Ngondi et al. 2009, Ngondi et al. 2005).
Helps support healthy cholesterol levels/cardiovascular health by reducing total and LDL cholesterol [Source note 2].
Helps support healthy glucose levels [Source note 3].
Source of antioxidants/Provides antioxidants [Source note 4].
Source of antioxidants/Provides antioxidants that help fight/protect (cell) against/reduce (the oxidative effect of/the oxidative damage caused by/cell damage caused by) free radicals [Source note 5].
Note: The above claims can be combined on the product label (e.g. Helps support healthy cholesterol levels by reducing total and LDL cholesterol and healthy glucose levels).
Who does this guide cover?
Adults 18 years and older
How is it taken?
Oral
Which forms are covered?
this reference excludes foods or food-like dosage forms as indicated in the Compendium of references Guidance Document.
Quantities
Weight management, cholesterol, glucose
Methods of preparation: Standardized Dry Extracts
150 milligrams of dry extract standardized to 7% albumin, 2 times per day (Ross 2011; Ngondi et al. 2009; Oben et al. 2008a, b).
Antioxidant
Methods of preparation: Dry, Powdered, Non-Standardized Extracts (Dry extract, Tincture, Fluid extract, Decoction, Infusion)
Not to exceed 3.15 grams of dried seed, per day [Source note 6].
How is it used?
Weight management, cholesterol, glucose
Take before meals (Ross 2011; Ngondi et al. 2009; Oben et al. 2008a,b; Ngondi et al. 2005; Adamson et al. 1986).
How long is it used?
The reference does not require an additional label statement in this section. This does not establish an absence of risk.
Warnings and precautions
All products
Ask a healthcare professional before use if you are breastfeeding.
Ask a healthcare professional before use if you have diabetes [Source note 7].
Antioxidant, cholesterol, glucose
Ask a healthcare professional before use if you are pregnant.
When should it be avoided?
Weight management
Do not use if you are pregnant.
Possible side effects
Stop use if you experience symptoms of hypoglycaemia including feelings of anxiety, dizziness, tremor, sweating, nausea or headache (Adamson et al. 1986; Ngondi et al. 2009; Oben et al. 2008a,b).
Storage
Must be established in accordance with the requirements described in the applicable product regulations.
Restrictions when this reference is combined with other references (source review category II and III):
If a weight management claim is made:
Preparation details
Ingredient identity, preparation requirements, and other details that define the scope of this guide.
Ingredients and preparations
| Proper name(s) | Common name(s) | Source information / Source material(s) | Source information / Part(s) | Source information / Preparation(s) |
|---|---|---|---|---|
| Irvingia gabonensis | African wild mango | Irvingia gabonensis | Seed | Dry |
References: Proper name: USDA 2023; Common name: USDA 2023; Source information: Ross 2011, Ngondi et al. 2009, Oben et al. 2008a, b, Ekpo et al. 2007, Ngondi et al. 2005.
Other ingredients
Must be chosen from the current source ingredient database and must meet the limitations outlined in the database.
Preparation and quality requirements
The finished product specifications must be established in accordance with the requirements described in the source authority source’s product quality guidance.
The active ingredient must comply with the requirements outlined in the source ingredient database.
Guide change history
Updates to this SupplementSafety.org guide.
Minor updates
Updated guide wording, organization, and source presentation. Added our editorial change history.
Initial release
Initial SupplementSafety.org guide prepared from source reference material.
Validation: Not yet completed. Editorial updates do not constitute clinical validation.
Sources
Source information
This guide organizes source material about uses, preparations, amounts, and precautions. Read the conditions alongside each statement; the information may apply only to particular preparations or populations.
The source document includes supporting references. We have not independently summarized or assessed every cited study for this guide.
- Source document version
- August 29, 2025
- Source captured
- Aug 15, 2026
- Editorial work
- Editorial preparation. Independent clinical review has not been recorded for this guide.
Full citations are available through the link above. Verification is required to open them; reading this guide does not require verification.
Taking a medication too?
Explore our supplement–medication interaction checker. Its coverage and review status are shown with the results; a missing finding does not establish that a combination is safe.