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Discuss melatonin with the alprazolam prescriber. General product guidance warns about extra sedation, but a small direct trial did not find worse measured sedation than alprazolam alone.
Read the interaction guide →Review melatonin before adding it to amoxapine, especially if you already feel sleepy. Amoxapine can impair alertness, but exact combination effects have not been measured in the sources reviewed.
Read the interaction guide →Review melatonin before adding it to aripiprazole lauroxil, especially if you already feel sleepy, dizzy or unsteady. The exact combination’s risk has not been quantified.
Read the interaction guide →Melatonin may add to butorphanol-related drowsiness and impairment. The exact combination has not been shown to produce a particular adverse-event rate, but the sedating effects warrant review before co-use.
Read the interaction guide →Melatonin may add to carbinoxamine-related sleepiness or impairment. Review the dose and formulation, particularly if you already feel drowsy; the exact combination’s risk has not been quantified.
Read the interaction guide →Review melatonin before adding it to cariprazine, especially if you already feel sleepy, dizzy or unsteady. The exact combination’s risk has not been quantified.
Read the interaction guide →Ask your prescriber before adding melatonin to chlordiazepoxide. Melatonin product information supports an alertness precaution, but it does not quantify this exact combination’s risk.
Read the interaction guide →Melatonin may add to chlorpromazine-related sleepiness. The exact clinical risk is not quantified, and laboratory or animal studies do not establish a safe dose or timing plan.
Read the interaction guide →Melatonin may add to chlorzoxazone-related drowsiness or impaired alertness. Review the exact product and other sedating medicines before adding it; this combination’s risk has not been measured directly.
Read the interaction guide →Review melatonin before adding it to citalopram, especially with opioids or other medicines affecting alertness. Severe sedation has been reported in a multi-medicine regimen.
Read the interaction guide →A matching name can refer to different products or preparations. Check the scope of the page you open. An absent result does not establish safety.
Sources, dates, and coverage →